Volume 9, Number 3 (september 2012)                   IJMSE 2012, 9(3): 49-57 | Back to browse issues page


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Darehkordi A, Hosseini M S. Montmorillonite modified as an efficient and environment friendly catalyst for one- pot synthesis of 3, 4-dihydropyrimidine-2(1H) ones. IJMSE. 2012; 9 (3) :49-57
URL: http://ijmse.iust.ac.ir/article-1-242-en.html

Abstract:   (3182 Views)
Montmorillonite modified is an efficient environmental friendly catalyst under one-pot-three-component synthesis of 3,4-dihydropyrimidine-2(1H) ones. The preparation was performed with an aldehyde, 1,3-dicarbonyl compounds, urea or thiourea under solvent-free conditions. In comparison with the other methods of Biginelli reaction, this new method has short reaction time inexpensive catalyst and in addition excellent yields were obtained.
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